Christopher Kline

Lab Manager

Christopher Kline



541 Bridgeside Point II

450 Technology Drive

Pittsburgh, PA 15219


BA in Anthropology, Pennsylvania State University, 2002

Research Lab Affiliation

Lab Role

Lab Manager

Areas of Interest

Molecular Biology, Next-Gen Sequencing


Akiyama H, Ramirez N.P, Gibson G, Kline C, Watkins S, Ambrose Z and Gummulura S. 2017. Interferon-Inducible CD169/Siglec1 Attenuates Anti-HIV-1 Effects of Alpha Interferon. J Virol. 91. |  View Abstract

Feder A.F, Kline C, Polacino P, Cottrell M, Kashuba A.D.M, Keele B.F, Hu S.L, Petrov D.A, Pennings P.S. and Ambrose Z. 2017. A spatio-temporal assessment of simian/human immunodeficiency virus (SHIV) evolution reveals a highly dynamic process within the host. PLoS Pathog. 13: e1006358. |  View Abstract

Kearney M.F, Anderson E.M, Coomer C, Smith L, Shao W, Johnson N, Kline C, Spindler J, Mellors, J.W, Coffin J.M. and Ambrose Z. 2015. Well-mixed plasma and tissue viral populations in RT-SHIV-infected macaques implies a lack of viral replication in the tissues during antiretroviral therapy. Retrovirology. 12: 93. |  View Abstract

Melody K, McBeth S, Kline C, Kashuba A.D, Mellors J.W. and Ambrose Z. 2015. Low Frequency of Drug-Resistant Variants Selected by Long-Acting Rilpivirine in Macaques Infected with Simian Immunodeficiency Virus Containing HIV-1 Reverse Transcriptase. Antimicrob Agens Chemother. 59: 7762-7770. |  View Abstract

Ambrose Z, Kline C, Polacino P and Hu SL. 2014. Dysregulation of multiple inflammatory molecules in lymph node and ileum of macaques during RT-SHIV infection with or without antiretroviral therapy. J Med Primatol. 43: 298-309. |  View Abstract

Kline C, Ndjomou J, Franks T, Kiser R, Coalter V, Smedley J, Piatak M. Jr, Mellors JW, Lifson JD and Ambrose Z. 2013. Persistence of viral reservoirs in multiple tissues after antiretroviral therapy suppression in a macaque RT-SHIV model. PLoS One. 8: e84275. |  View Abstract