Wen Meng, PhD
- Research Assistant Professor
Education & Training
- Post doc, University of Pittsburgh 2023
- PhD in Veterinary Biotechnology, China Agriculture University, 2018
- BS in Veterinary Medicine, China Agriculture University, 2013
Research Interest Summary
Research Interests
1. Studying tumor microenviroment using Spatial Single-Cell In-Situ Transcriptomic Analysis (SSTA).
2. Mechanisms regulating the infection, replication and cellular transformation of tumor viruses, with emphasis on RNA modifications and machinery.
Publications
Zhang X, Meng W, Feng J, Gao X, Qin C, Feng P, Huang Y, Gao SJ. 2023. METTL16 controls Kaposi's sarcoma-associated herpesvirus replication by regulating S-adenosylmethionine cycle. Cell Death Dis.14, 9:591. doi: 10.1038/s41419-023-06121-3 | View abstract
Das A1, Meng W1, Liu Z, Hasib MM, Galloway H, Ramos da Silva S, Chen L, Sica GL, Paniz-Mondolfi A, Bryce C, Grimes Z, Sordillo EM, Cordon-Cardo C, Rivera KP, Flores M, Chiu YC, Huang Y, Gao SJ. 2023. Molecular and immune signatures, and pathological trajectories of fatal COVID-19 lungs defined by in situ spatial single-cell transcriptome analysis. J Med Virol. 95, 8:e29009. doi: 10.1002/jmv.29009 | View abstract
Meng W, Guo S, Cao S, Shuda M, Robinson-McCarthy LR, McCarthy KR, Shuda Y, Paniz Mondolfi AE, Bryce C, Grimes Z, Sordillo EM, Cordon-Cardo C, Li P, Zhang H, Perlman S, Guo H, Gao SJ, Chang Y, Moore PS. 2023. Development and characterization of a new monoclonal antibody against SARS-CoV-2 NSP12 (RdRp). J Med Virol. 95,1:e28246. doi: 10.1002/jmv.28246 | View abstract
Markazi A, Meng W, Bracci PM, McGrath MS, Gao SJ. 2021. The role of bacteria in KSHV infection and KSHV-induced cancers. Cancers (Basel). 13,17:4269. doi: 10.3390/cancers13174269 | View abstract
Meng W, Gao SJ. 2021. Targeting XPO1 enhances innate immune response and inhibits KSHV lytic replication during primary infection by nuclear stabilization of the p62 autophagy adaptor protein. Cell Death Dis.12,1:29 doi: 10.1038/s41419-020-03303-1 | View abstract