Hannah Priyadarshini Gideon, PhD

Research Instructor


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Contact

412-624-8664
Fax: 412-648-9076

5065 Biomedical Science Tower 3

3501 Fifth Avenue

Pittsburgh, PA 15260

Education

PhD in Medical Microbiology, University of Cape Town, South Africa, 2010

MSc in Medical Microbiology, Kasturba Medical College, Manipal Academy of Higher Education, India, 2004

BSc in Medical Microbiology, Mother Teresa Women's University, India, 2001

Research Lab Affiliation

Areas of Interest

T cell immunology in Tuberculosis in humans and animal models (Non-human primates and Murine) Understanding host pathogen relationship at both local (granuloma) and systemic levels, T cell function and its modulation, systems biology and whole genome blood transcriptional profiling of Mycobacterium tuberculosis infection in Non-human primates.

Publications

Gideon H.P, Phuah J, Myers A.J, Bryson B.D, Rodgers M.A, Coleman M.T, Maiello P, Rutledge T, Marino S, Fortune S.M, Kirschner D.E, Lin P.L. and Flynn J.L. (2015) Variability in tuberculosis granuloma T cell responses exists, but a balance of pro- and anti-inflammatory cytokines is associated with sterilization. PLoS Pathog 11: e1004603. |  View Abstract

Gideon H.P, Hamilton M.S, Wood K, Pepper D, Oni T, Seldon R, Banwell C, Langford P.R, Wilkinson R.J. and Wilkinson K.A. (2013) Impairment of IFN-gamma response to synthetic peptides of Mycobacterium tuberculosis in a 7-day whole blood assay. PLoS One. 8: e71351. |  View Abstract

Gideon H.P, Wilkinson K.A, Rustad T.R, Oni T, Guio H, Sherman D.R, Vordermeier H.M, Robertson B.D, Young D.B. and Wilkinson R.J. (2012) Bioinformatic and empirical analysis of novel hypoxia-inducible targets of the human antituberculosis T cell response. J Immunol. 198: 5867-5876. |  View Abstract

Lin, P. L; Dietrich, J; Tan, E; Abalos, R. M; Burgos, J; Bigbee, C; Bigbee, M; Milk, L; Gideon, H. P; Rodgers, M; Cochran, C; Guinn, K. M; Sherman, D. R; Klein, E; Janssen, C; Flynn, J. L; and Andersen, P. (2012) The multistage vaccine H56 boosts the effects of BCG to protect cynomolgus macaques against active tuberculosis and reactivation of latent Mycobacterium tuberculosis infection. J Clin Invest. 122: 303-314. |  View Abstract

Rangaka M.X, Gideon H.P, Wilkinson K.A, Pai M, Mwansa-Kambafwile J, Maartens G, Glynn J.R, Boulle A, Fielding K, Goliath R, Titus R, Mathee S. and Wilkinson R.J. (2012) Interferon release does not add discriminatory value to smear-negative HIV-tuberculosis algorithms. Eur Respir J. 39: 163-171. |  View Abstract

Gideon H.P, Wilkinson K.A, Rustad T.R, Oni T, Guio H, Kozak R.A, Sherman D.R, Meintjes G, Behr M.A, Vordermeier H.M, Young D.B. and Wilkinson R.J. (2010) Hypoxia induces an immunodominant target of tuberculosis specific T cells absent from common BCG vaccines. PLoS Pathog. 6: e1001237. |  View Abstract

Young D.B, Gideon H.P. and Wilkinson R.J. (2009) Eliminating latent tuberculosis. Trends Microbiol. 17: 183-188. |  View Abstract