Berthony Deslouches, MD, PhD

Research Assistant Professor


Dr. Deslouches

Contact

412-648-8874
Fax: 412-624-4440

9026 Biomedical Science Tower 3

3501 Fifth Avenue

Pittsburgh, PA 15261

Education

MD, PhD, Univeristy of Pittsburgh, 2008

MA in Biochemistry, City College of the City University of New York, 1995

BS in Anthropology and Biochemistry, City College of the City University of New York, 1993

Research Summary

Our research focuses on the development of engineered antimicrobial peptides (eCAPs) for applications to hard-to-treat bacterial infections, particularly infections caused by multidrug-resistant pathogens.

Research Lab Affiliation

Why I Chose Pitt

I graduated from University of Pittsburgh School of Medicine. I know this is a great institution!

Publications

Neal, M. D; Deslouches, B; and Ogilvie, J. (2009) The use of pre-operative imaging and intraoperative parathyroid hormone level to guide surgical management of tertiary hyperparathyroidism from X-linked hypophosphatemic rickets: a case report. Cases J. 2: 7572. |  View Abstract

Deslouches, B; Gonzalez, I. A; DeAlmeida, D; Islam, K; Steele, C; Montelaro, R. C; and Mietzner, T. A. (2007) De novo-derived cationic antimicrobial peptide activity in a murine model of Pseudomonas aeruginosa bacteraemia. J Antimicrob Chemother. 60: 669-672. |  View Abstract

Phadke, S. M; Deslouches, B; Hileman, S. E; Montelaro, R. C; Wiesenfeld, H. C; and Mietzner, T. A. (2005) Antimicrobial peptides in mucosal secretions: the importance of local secretions in mitigating infection. J Nutr. 135: 1289-1293. |  View Abstract

Deslouches, B; Phadke, S. M; Lazarevic, V; Cascio, M; Islam, K; Montelaro, R. C; and Mietzner, T. A. (2005) De novo generation of cationic antimicrobial peptides: influence of length and tryptophan substitution on antimicrobial activity. Antimicrob Agents Chemother. 49: 316-322. |  View Abstract

Deslouches, B; Islam, K; Craigo, J. K; Paranjape, S. M; Montelaro, R. C; and Mietzner, T. A. (2005) Activity of the de novo engineered antimicrobial peptide WLBU2 against Pseudomonas aeruginosa in human serum and whole blood: implications for systemic applications. Antimicrob Agents Chemother. 49: 3208-3216. |  View Abstract

Phadke, S. M; Islam, K; Deslouches, B; Kapoor, S. A; Beer Stolz, D; Watkins, S. C; Montelaro, R. C; Pilewski, J. M; and Mietzner, T. A. (2003) Selective toxicity of engineered lentivirus lytic peptides in a CF airway cell model. Peptides. 24: 1099-1107. |  View Abstract

Li, J; Deslouches, B; Cosloy, S. D; and Russell, C. S. (2003) A heme-deficient strain of Escherichia coli has a three-base pair deletion in a "hotspot" in hemA. Biochim Biophys Acta. 1626: 102-105. |  View Abstract